PHR1663 Supelco


Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 2,6-Bis(1-methylethyl)phenol, 2,6-Bis(isopropyl)phenol, 2,6-Diisopropylphenol, Propofol



Related Categories Analytical Standards, Analytical/Chromatography, P-S, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor pressure   5.6 mmHg ( 100 °C)
packaging   ampule of 1 mL
refractive index   n20/D 1.514 (lit.)
bp   256 °C/764 mmHg (lit.)
mp   18 °C (lit.)
density   0.962 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to BP 1031
  traceable to PhEur Y0000016
  traceable to USP 1572503


General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propofol is approved for induction and maintenance of paediatric anesthesia and sedation in children less than 3 years of age. The mechanism of action involves interaction with gamma-aminobutyric acid A receptor. Rapid effect and fewer side effects like postoperative nausea makes propofol a popular intravenous anesthetic agents.


These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Propofol may be used as a pharmaceutical reference standard for the determination of the analyte in emulsion dosage form by sequential injection technique with spectrophotometric and fluorimetric detections.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


To see an example of a Certificate of Analysis for this material enter LRAA5999 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

NONH for all modes of transport
Protocols & Articles
Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?