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PHR1732 Supelco

Vancomycin hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Vancomycin hydrochloride

  • CAS Number 1404-93-9

  • Empirical Formula (Hill Notation) C66H75Cl2N9O24 · xHCl

  • Molecular Weight 1449.25 (free base basis)

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards, T-Z More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
packaging   pkg of 4x250 mg
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur V0045000
  traceable to USP 1709007

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Vancomycin hydrochloride is a glycopeptide antibiotic, effective for the treatment of endocarditis caused by Gram-positive bacteria. It is used to inhibit the synthesis of bacterial cell wall and prevents the synthesis of peptidoglycan by binding tightly to peptides containing D-alanyl-D-alanine at the free carboxyl end. It is isolated from both Streotomyces orientalis and Nocardia lurida.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Vancomycin hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, pure form and injections preparations using high-performance liquid chromatography technique and spectrophotometric technique.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0718 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

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