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PHR1748 Supelco

Glacial Acetic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Acetic acid, Glacial acetic acid

  • CAS Number 64-19-7

  • Linear Formula CH3CO2H

  • Molecular Weight 60.05

  •  Beilstein/REAXYS Number 506007

  •  EC Number 200-580-7

  •  MDL number MFCD00036152

  •  PubChem Substance ID 329823593

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, E-J, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor density   2.07 (vs air)
InChI Key   QTBSBXVTEAMEQO-UHFFFAOYSA-N
autoignition temp.   800 °F
expl. lim.   16 %, 92 °F
  4 %, 59 °F
packaging   ampule of 3x1.5 mL
refractive index   n20/D 1.371 (lit.)
bp   117-118 °C (lit.)
mp   16.2 °C (lit.)
density   1.049 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1005706

Description

General description

Glacial Acetic Acid is a simple monocarboxylic acid, which is devoid of water. Pharmaceutically, it is commonly used as a topical antibiotic that treats infections caused by bacteria.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Glacial Acetic Acid may be used as a reference standard for the determination of the analyte in raw materials and pharmaceutical formulations by titrimetry and gas chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2954 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
UN 2789PSN1 3(8) / PGII
Protocols & Articles

Articles

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GC Analysis of C2-C7 Free Fatty Acids on Nukol™

From our library of Articles, Sigma-Aldrich presents GC Analysis of C2-C7 Free Fatty Acids on Nukol™
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on Equity®-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on Equity®-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on OVI-G43

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on OVI-G43
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Fermentation Compounds on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack™ B AW)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Fermentation Compounds on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack™ B AW)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Free Fatty Acids in Parmesan Cheese using Nukol™ after SPME using 65 μm Carbowax/DVB Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Free Fatty Acids in Parmesan Cheese using Nukol™ after SPME using 65 μm Carbowax/DVB Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Solid phase microextractions

GC Analysis of Fresh and Rancid Potato Chips on SPB®-1 SULFUR after SPME using 50/30 μm DVB/Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Fresh and Rancid Potato Chips on SPB®-1 SULFUR after SPME using 50/30 μm DVB/Carboxen/PDMS Fiber
Keywords: AGE, Chromatin immunoprecipitation, Chromatography, Gas chromatography, Mass spectrometry, Oxidations, Purification, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Scotch Whiskey on a Packed Column (5% Carbowax® 20M on 80/120 °Carbopack B)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Scotch Whiskey on a Packed Column (5% Carbowax® 20M on 80/120 °Carbopack B)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Scotch Whiskey on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack B AW)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Scotch Whiskey on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack B AW)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Volatiles in PVC Pipe on SPB®-HAP after Collection/Desorption using Carbotrap® 300 Tube

From our library of Articles, Sigma-Aldrich presents GC Analysis of Volatiles in PVC Pipe on SPB®-HAP after Collection/Desorption using Carbotrap® 300 Tube
Keywords: Air Monitoring, Chromatography, Gas chromatography, Purification

GC Analysis of Volatiles in White Wine on VOCOL® after SPME using a 75 μm Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Volatiles in White Wine on VOCOL® after SPME using a 75 μm Carboxen/PDMS Fiber
Keywords: Chromatography, Gas chromatography, Gas chromatography mass spectrometry, Mass spectrometry, Purification, Solid phase microextractions

HPLC Analysis of Organic Acids Commonly Found in Wine and Beer on TSKgel® OApak-P and OApak-A

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Organic Acids Commonly Found in Wine and Beer on TSKgel® OApak-P and OApak-A
Keywords: Chromatography, High performance liquid chromatography

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