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PHR1857 Supelco

Sitagliptin Phosphate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate, MK-0431, Sitagliptin phosphate monohydrate

  • CAS Number 654671-77-9

  • Empirical Formula (Hill Notation) C16H15F6N5O · H3PO4 · H2O

  • Molecular Weight 523.32

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, P-S, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
packaging   pkg of 1 g
Featured Industry   Pharmaceutical (small molecule)
pharmacopeia traceability   traceable to PhEur Y0001812
  traceable to USP 1612903

Description

General description

An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates insulin release and lowers blood glucose.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0251 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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