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PHR2303 Supelco

Ropivacaine hydrochloride

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Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate, (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate, Naropin hydrochloride monohydrate, Ropivacaine hydrochloride monohydrate

  • CAS Number 132112-35-7

  • Empirical Formula (Hill Notation) C17H26N2O · HCl · H2O

  • Molecular Weight 328.88

  •  MDL number MFCD00946578

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Properties

grade   certified reference material
  pharmaceutical secondary standard
packaging   pkg of 500 mg
pharmacopeia traceability   traceable to PhEur Y0000742
  traceable to USP 1605500
SMILES string   O.Cl.CCCN1CCCC[C@H]1C(=O)Nc2c(C)cccc2C
InChI   1S/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2/t15-;;/m0../s1
InChI key   VSHFRHVKMYGBJL-CKUXDGONSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Biochem/physiol Actions

Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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