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R0300000

Retinol acetate

European Pharmacopoeia (EP) Reference Standard

Synonym: Retinol acetate, Retinyl acetate, Vitamin A acetate

  • CAS Number 127-47-9

  • Empirical Formula (Hill Notation) C22H32O2

  • Molecular Weight 328.49

  •  Beilstein/REAXYS Number 1915439

  •  MDL number MFCD00019413

  •  PubChem Substance ID 329823984

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards P - R, Pharmacopeia & Metrological Institutes Standards More...
biological source   synthetic
grade   pharmaceutical primary standard
Agency/Method   EP
form   neat
mfr. no.   EDQM
mp   57-58 °C
Featured Industry   Pharmaceutical (small molecule)
format   neat
storage temp.   −20°C
SMILES string   CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
InChI   1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
InChI key   QGNJRVVDBSJHIZ-QHLGVNSISA-N

Description

General description

This product is provided as delivered and specified by the issuing pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the authority of the issuing pharmacopoeia. For further information and support please go to the website of the issuing pharmacopoeia. Retinyl Acetate belongs to the class of compounds called retinoids, which are chemically related to vitamin A. Retinoids are employed in the management of acne and psoriasis through oral and topical administration.

Application

Retinol acetate may be used as an analytical reference standard for the quantification of the analyte in capsules using reversed-phase high-performance liquid chromatography technique.

Packaging

Unit quantity: 500 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Fat Soluble (A and E), on Discovery® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Fat Soluble (A and E), on Discovery® C8
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

UHPLC Analysis of Fat Soluble Vitamins on Titan™ C18, Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Fat Soluble Vitamins on Titan™ C18, Acetonitrile Mobile Phase
Keywords: Chromatography, Vitamins

UHPLC Analysis of Fat Soluble Vitamins on Titan™ C18, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Fat Soluble Vitamins on Titan™ C18, Methanol Mobile Phase
Keywords: Chromatography, Vitamins

Peer-Reviewed Papers
15

References

Related Products

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PHR1236 Retinyl Acetate (Vitamin A Acetate), Pharmaceutical Secondary Standard; Certified Reference Material
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