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S0765000 Sigma-Aldrich

Diclofenac sodium

European Pharmacopoeia (EP) Reference Standard

Synonym: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt, Diclofenac sodium salt

  • CAS Number 15307-79-6

  • Empirical Formula (Hill Notation) C14H10Cl2NNaO2

  • Molecular Weight 318.13

  •  MDL number MFCD00082251

  •  PubChem Substance ID 329824440

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Diclofenac,
InChI Key   KPHWPUGNDIVLNH-UHFFFAOYSA-M
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Standard NSAID and cyclooxygenase (COX) inhibitor. Major metabolites are 4´-hydroxydiclofenac and 5´-hydroxydiclofenac. Has been used as substrate selective for CYP2C9.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
UN 2811 6.1 / PGIII

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

European Pharmacopoeia Method for Diclofenac Identification Test B using Silica Gel G TLC plates

Diclofenac sodium is a non-steroidal anti-inflammatory (NSAID) drug. It is used to treat pain, inflammatory disorders, and dysmenorrhea.
Dr. Sanjay Poman
Merck KGaA, Darmstadt, Germany, Life Science Application Centre (GAC), Mumbai, India
Keywords: Anti-inflammatory agents, Indicators, Thin layer chromatography

LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips
Keywords: Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Separation, Solid phase microextractions

Peer-Reviewed Papers
15

References

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PHR1144 Diclofenac sodium salt, Pharmaceutical Secondary Standard; Certified Reference Material
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