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S0929 Sigma-Aldrich

Scopolamine hydrobromide

meets USP testing specifications

Synonym: (−)-Scopolamine hydrobromide trihydrate, Hyoscine hydrobromide, Scopine tropate

  • CAS Number 6533-68-2

  • Empirical Formula (Hill Notation) C17H21NO4 · HBr · 3H2O

  • Molecular Weight 438.31

  •  Beilstein/REAXYS Number 6100669

  •  MDL number MFCD00150066

  •  PubChem Substance ID 24899453

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Properties

Related Categories Analytical/Chromatography, Core Bioreagents, Enzyme Inhibitors, Pharmacopoeia, Pharmacopoeia A-Z,
InChI Key   LACQPOBCQQPVIT-SEYKEWMNSA-N
mp   195-199 °C (dry matter) (lit.)
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)

Description

Application

Scopolamine hydrobromide has been used as a muscarinic receptor antagonist:
• to reverse the cardiac effects of physostigmine in rabbit heart
• to study its effect on acoustic startle reflex (gap-PPI){148)
• to study it’s in vitro antiviral, antibacterial, and antifungal activities and cytotoxicity
• to study its effect on conditioning of lever pressing

Packaging

1, 5, 25 g in glass bottle

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1544PSN2 6.1 / PGIII
WGK Germany 
1
RTECS 
YM4730000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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