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S1400000 Sigma-Aldrich

Streptomycin sulfate

European Pharmacopoeia (EP) Reference Standard

Synonym: Streptomycin sulfate salt

  • CAS Number 3810-74-0

  • Linear Formula C21H39N7O12 · 1.5 H2SO4

  • Molecular Weight 728.69

  •  Beilstein/REAXYS Number 3894995

  •  MDL number MFCD00037023

  •  PubChem Substance ID 329824477

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards S - T, Pharmacopeia & Metrological Institutes Standards More...
InChI Key   QTENRWWVYAAPBI-YZTFXSNBSA-N
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat
shipped in   wet ice
storage temp.   −20°C

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.

Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.

Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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