S7795 Sigma-Aldrich

Sodium carbonate

BioXtra, ≥99.0%

Synonym: Calcined soda, Carbonic acid disodium salt, Soda ash



Related Categories Acids & Bases, Bases, Biochemicals and Reagents, Biological Buffers, Buffered Salt Solutions,
Quality Level   200
product line   BioXtra
assay   ≥99.0%
form   powder
impurities   ≤0.02% Phosphorus (P)
  ≤0.1% Insoluble matter
pH   11.2 (25 °C, 4 g/L)
mp   851 °C (lit.)
solubility   H2O: 1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.02%
cation traces   Al: ≤0.001%
  Ca: ≤0.02%
  Cu: ≤0.0005%
  Fe: ≤0.001%
  K: ≤0.005%
  Mg: ≤0.005%
  NH4+: ≤0.05%
  Pb: ≤0.001%
  Zn: ≤0.0005%
SMILES string   O=C(O[Na])O[Na]
InChI   1S/CH2O3.2Na/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2


General description

Sodium carbonate is usually referred to as soda ash. Solvay process uses sodium chloride and limestone to produce sodium carbonate. Sodium carbonate enhances the pretreatment of rice straw and enhances delignification process. Sodium carbonate finds its application in the extraction of bioactive metabolites like epoxyditerpenoids and alkaloids and removes acidic compounds from the extract. Sodium carbonate induces the phase separation in salt induced phase separation extraction (SIPSE) method and enhances the plasma partitioning with acetonitrile.


Sodium carbonate has been used:
• to stop α-glucosidase enzyme activity using the extract of Terminalia species
• as a component in carbonate/bicarbonate buffer for enzyme linked immunosorbent assay (ELISA)
• as a component in the growth medium for Synechocystis strains


1 kg in poly bottle

500 g in poly bottle

Biochem/physiol Actions

Buffer component, may be used for the removal of peripheral membrane proteins.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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