S7795 Sigma-Aldrich

Sodium carbonate

BioXtra, ≥99.0%

Synonym: Calcined soda, Carbonic acid disodium salt, Soda ash

  • CAS Number 497-19-8

  • Linear Formula Na2CO3

  • Molecular Weight 105.99

  •  Beilstein Registry Number 4154566

  •  EC Number 207-838-8

  •  PubChem Substance ID 24899762



Related Categories Acids & Bases, Bases, Biochemicals and Reagents, Biological Buffers, Buffered Salt Solutions,
product line   BioXtra
assay   ≥99.0%
form   powder
impurities   ≤0.02% Phosphorus (P)
  ≤0.1% Insoluble matter
mp   851 °C (lit.)
solubility   H2O: 1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.02%
cation traces   Al: ≤0.001%
  Ca: ≤0.02%
  Cu: ≤0.0005%
  Fe: ≤0.001%
  K: ≤0.005%
  Mg: ≤0.005%
  NH4+: ≤0.05%
  Pb: ≤0.001%
  Zn: ≤0.0005%


Biochem/physiol Actions

Buffer component, may be used for the removal of peripheral membrane proteins.


1 kg in poly bottle

500 g in poly bottle


Sodium carbonate has been used:
• to stop α-glucosidase enzyme activity using the extract of Terminalia species
• as a component in carbonate/bicarbonate buffer for enzyme linked immunosorbent assay (ELISA)
• as a component in the growth medium for Synechocystis strains

General description

Sodium carbonate is usually referred to as soda ash. Solvay process uses sodium chloride and limestone to produce sodium carbonate. Sodium carbonate enhances the pretreatment of rice straw and enhances delignification process. Sodium carbonate finds its application in the extraction of bioactive metabolites like epoxyditerpenoids and alkaloids and removes acidic compounds from the extract. Sodium carbonate induces the phase separation in salt induced phase separation extraction (SIPSE) method and enhances the plasma partitioning with acetonitrile.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

High Quality GMP-Buffers

Protein Stabilizer
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