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S7920 Sigma-Aldrich

Sodium fluoride

BioXtra, ≥99%

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Properties

Related Categories Chemical Synthesis, Core Bioreagents, General Reagents, Inorganic Salts, Life Science Reagents for Protein Expression and Purification,
vapor pressure   1.4 mmHg ( 0 °C)
InChI Key   PUZPDOWCWNUUKD-UHFFFAOYSA-M
product line   BioXtra
assay   ≥99%
impurities   ≤0.0005% Phosphorus (P)
  ≤0.1% Insoluble matter
mp   993 °C (lit.)
solubility   H2O: 1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.005%
  sulfate (SO42-): ≤0.03%
cation traces   Al: ≤0.001%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.003%
  K: ≤0.005%
  Mg: ≤0.0005%
  NH4+: ≤0.1%
  Pb: ≤0.001%
  Zn: ≤0.0005%

Description

Packaging

100, 500 g in poly bottle

Application

Sodium fluoride has been used:
• as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
• as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
• as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Biochem/physiol Actions

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Contact with acids liberates very toxic gas.
RIDADR 
UN 1690 6.1 / PGIII
WGK Germany 
1
RTECS 
WB0350000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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