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S9251 Sigma-Aldrich

Sulfanilamide

≥98%

Synonym: p-Aminobenzenesulfonamide

  • CAS Number 63-74-1

  • Linear Formula H2NC6H4SO2NH2

  • Molecular Weight 172.20

  •  Beilstein/REAXYS Number 511852

  •  EC Number 200-563-4

  •  MDL number MFCD00007939

  •  eCl@ss 39093202

  •  PubChem Substance ID 24899829

  •  NACRES NA.76

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action,
Quality Level   200
assay   ≥98%
form   powder or crystals
color   white to off-white
mp   164-166 °C (lit.)
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
SMILES string   Nc1ccc(cc1)S(N)(=O)=O
InChI   1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChI key   FDDDEECHVMSUSB-UHFFFAOYSA-N
Gene Information   human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
mouse ... Car13(71934), Car5a(12352)

Description

General description

Chemical structure: sulfonamide

Packaging

100, 500 g in poly bottle

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: A competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
WO8400000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Related Content

Antibiotics Selection Guide

The Antibiotic Selection Guide enables researchers to spend more time on their research discoveries and less time seeking established antibiotic information. Link to hundreds of antibiotics for conta...
Keywords: Antibiotics, Cell biology, Cell culture, Genetic, High performance liquid chromatography, Reversed-phase chromatography

Peer-Reviewed Papers
15

References

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