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T4625 Sigma-Aldrich

Thiamine hydrochloride

reagent grade, ≥99% (HPLC)

Synonym: Aneurine hydrochloride, Vitamin B1 hydrochloride

  • CAS Number 67-03-8

  • Empirical Formula (Hill Notation) C12H17ClN4OS · HCl

  • Molecular Weight 337.27

  •  Beilstein/REAXYS Number 3851771

  •  EC Number 200-641-8

  •  MDL number MFCD00012780

  •  eCl@ss 34058006

  •  PubChem Substance ID 24900057

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cofactors, Core Bioreagents, Enzymes, Inhibitors, and Substrates,
Quality Level   200
biological source   synthetic (organic)
grade   reagent grade
InChI Key   DPJRMOMPQZCRJU-UHFFFAOYSA-M
assay   ≥99% (HPLC)
form   powder
application(s)   HPLC: suitable
color   white
mp   250 °C (dec.) (lit.)
solubility   H2O: 50 mg/mL, clear, colorless

Description

General description

Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs.

Application

Thiamine hydrochloride has been used as a vitamin supplement to the holidic medium and in bacterial growth medium.

Packaging

1 kg in poly drum

5, 10, 25, 100, 250 g in poly bottle

Biochem/physiol Actions

Thiamine is an essential coenzyme in carbohydrate metabolism. Deficiency of thiamine causes beriberi, a neurological and cardiovascular disease. Thiamine is administered in case of deficiency, either due to reduced intake or synthesis. Congenital defect in the thiamine transporter gene SLC19A2 causes thiamine-responsive megaloblastic anemia syndrome (TRMA). Thiamine mimics acetylcholine in brain and possible exerts a role in Alzheimer′s disease. Thiamine deficiency in ruminants causes polioencephalomalacia.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
XI7350000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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