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T8656 Sigma-Aldrich

Thiourea

ACS reagent, ≥99.0%

Synonym: Sulfourea, Thiocarbamide

  • CAS Number 62-56-6

  • Linear Formula NH2CSNH2

  • Molecular Weight 76.12

  •  Beilstein/REAXYS Number 605327

  •  EC Number 200-543-5

  •  MDL number MFCD00008067

  •  PubChem Substance ID 24900549

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Properties

Related Categories Building Blocks, Chemical Synthesis, Core Bioreagents, General Reagents, Life Science Reagents for Protein Electrophoresis,
grade   ACS reagent
InChI Key   UMGDCJDMYOKAJW-UHFFFAOYSA-N
assay   ≥99.0%
ign. residue   ≤0.1% (as SO4)
loss   ≤0.5% loss on drying, 105°C, 2h
mp   170-176 °C (lit.)
  174-177 °C
solubility   H2O: passes test
Gene Information   mouse ... Ephx2(13850)

Description

General description

Thiourea is an analogue of urea containing sulphur.

Application

Thiourea has been used:
• as a component of lysis buffer for liver tissue homogenization
• in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay
• in rehydration buffer for protein extraction

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Packaging

50, 100, 500 g in poly bottle

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
YU2800000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Mesoporous Titanium Dioxide Thin Films

Titanium dioxide (TiO2) is an important n-type semiconducting material that shows interesting characteristics such as photoswitchable surface wettability, high photocatalytic activity, bistable elect...
Jinshu Wang, Junshu Wu, Hongyi Li
Material Matters, Volume 7, Number 2, 2–6
Keywords: Adsorption, Building blocks, Catalysis, Ceramics, Condensations, Cosmetics, Degradations, Diffraction, Eliminations, Evaporation, Materials Science, Oxidations, Polymerization reactions, Semiconductor, Separation, Sol-gel

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Peer-Reviewed Papers
15

References

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