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U5128 Sigma-Aldrich

Urea

ACS reagent, 99.0-100.5%

Synonym: Carbamide, Carbonyldiamide

  • CAS Number 57-13-6

  • Linear Formula NH2CONH2

  • Molecular Weight 60.06

  •  Beilstein/REAXYS Number 635724

  •  EC Number 200-315-5

  •  MDL number MFCD00008022

  •  PubChem Substance ID 24900652

  •  NACRES NA.21

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Properties

Related Categories Biochemicals and Reagents, Building Blocks, Carbonyl Compounds, Chaotropic Agents, Chemical Synthesis,
Quality Level   200
grade   ACS reagent
assay   99.0-100.5%
form   solid
impurities   ≤0.01% Insoluble matter
ign. residue   ≤0.01%
mp   132-135 °C (lit.)
solubility   H2O: soluble 480 g/L at 20 °C
density   1.335 g/mL at 25 °C (lit.)
anion traces   chloride (Cl-): ≤5 ppm
  sulfate (SO42-): ≤0.001%
cation traces   Fe: ≤0.001%
  heavy metals (as Pb): ≤0.001%
SMILES string   NC(N)=O
InChI   1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key   XSQUKJJJFZCRTK-UHFFFAOYSA-N
Gene Information   human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

Description

General description

Urea is a colourless organic compound, without any odour. It is easily soluble in water.

Application

Urea has been used:
• to adjust the urea nitrogen concentration to a preferred range in blood reservoir for evaluating the dialyzer urea clearance
• to prepare standards to measure urea synthesis
• to prepare standards for blood urea nitrogen assay

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Packaging

1 kg in poly bottle

5 kg in poly drum

5, 100, 500 g in poly bottle

Biochem/physiol Actions

Urea participates in the metabolism of nitrogenous substances. It serves as a nitrogen source, when used in fertilizers. Urea is used in manufacturing chemical compounds. It is widely used in the agricultural industry as a fertilizer as well as an animal feed additive, which is used as a nitrogen supplement in animal husbandry. Urea has adverse effects on seed germination, seedling growth and early plant growth in soil.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
YR6250000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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