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Y0000002

Acetylcholine chloride

European Pharmacopoeia (EP) Reference Standard

Synonym: ACh

  • CAS Number 60-31-1

  • Linear Formula (CH3)3N+CH2CH2OCOCH3Cl-

  • Molecular Weight 181.66

  •  Beilstein/REAXYS Number 3571875

  •  EC Number 200-468-8

  •  MDL number MFCD00011698

  •  PubChem Substance ID 329830811

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards A - B, Pharmacopeia & Metrological Institutes Standards More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   EDQM
mp   146-150 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   [Cl-].CC(=O)OCC[N+](C)(C)C
InChI   1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key   JUGOREOARAHOCO-UHFFFAOYSA-M
Gene Information   human ... CHRM3(1131)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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PHR1546 Acetylcholine chloride, Pharmaceutical Secondary Standard; Certified Reference Material

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