EMAIL THIS PAGE TO A FRIEND
Y0000306

Azithromycin

European Pharmacopoeia (EP) Reference Standard

Synonym: N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A, Azithromycin dihydrate, CP-62993

  • CAS Number 117772-70-0

  • Empirical Formula (Hill Notation) C38H72N2O12 · 2H2O

  • Molecular Weight 785.02

  •  MDL number MFCD01862248

  •  PubChem Substance ID 329830903

  •  NACRES NA.24

Purchase

Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards A - B, Pharmacopeia & Metrological Institutes Standards More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   EDQM
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   O.O.CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
InChI   1S/C38H72N2O12.2H2O/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28;;/h20-33,35,41-43,45-46H,15-19H2,1-14H3;2*1H2/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-;;/m1../s1
InChI key   SRMPHJKQVUDLQE-KUJJYQHYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.

Packaging

Unit quantity: 410 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Azithromycin on Ascentis® Express C18 5μm

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Azithromycin on Ascentis® Express C18 5μm
Keywords: Antibiotics, Chromatography, Derivatizations, High performance liquid chromatography, Pharmaceutical

LC/MS Analysis of Azithromycin on Titan™ C18

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Azithromycin on Titan™ C18
Keywords: Antibiotics, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

PHR1088 Azithromycin, Pharmaceutical Secondary Standard; Certified Reference Material
08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?