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Y0000543

Oxazepam for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym: 7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-1,4(2H)-benzodiazepin-2-one, Oxazepam

  • CAS Number 604-75-1

  • Empirical Formula (Hill Notation) C15H11ClN2O2

  • Molecular Weight 286.71

  •  MDL number MFCD00057903

  •  PubChem Substance ID 329831008

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards N - O, Pharmacopeia & Metrological Institutes Standards More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   EDQM
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   OC1N=C(c2ccccc2)c3cc(Cl)ccc3NC1=O
InChI   1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)
InChI key   ADIMAYPTOBDMTL-UHFFFAOYSA-N
Gene Information   human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Anxiolytic; ligand for the GABAA receptor benzodiazepine modulatory site.

Packaging

Unit quantity: 0.008 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Antianxiety Drugs on Ascentis® Express C18 vs. Standard C18, Demonstrating High Throughput on Ascentis Express

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antianxiety Drugs on Ascentis® Express C18 vs. Standard C18, Demonstrating High Throughput on Ascentis Express
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Antianxiety Drugs on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antianxiety Drugs on Ascentis® Phenyl
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Anxiolytic Drugs on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anxiolytic Drugs on Discovery® C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Anxiolytic Drugs on SUPELCOSIL™ LC-8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anxiolytic Drugs on SUPELCOSIL™ LC-8
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® Express C18, Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® Express C18, Acetonitrile Mobile Phase
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl with Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl with Acetonitrile Mobile Phase
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl, Methanol Mobile Phase
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Oxazepam Enantiomers on Astec® CHIROBIOTIC® T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Oxazepam Enantiomers on Astec® CHIROBIOTIC® T
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Oxazepam Enantiomers on Astec® CYCLOBOND® I 2000 DNP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Oxazepam Enantiomers on Astec® CYCLOBOND® I 2000 DNP
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

LC/MS Analysis of Benzodiazepines on Ascentis® Phenyl (Analyte Mix 1)

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Benzodiazepines on Ascentis® Phenyl (Analyte Mix 1)
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

UHPLC Analysis of Diazepam and Metabolites on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Diazepam and Metabolites on Ascentis® Express C18
Keywords: Chromatography, Clinical

UHPLC Analysis of Diazepam and Metabolites on Titan™ C18, Competitive Comparison

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Diazepam and Metabolites on Titan™ C18, Competitive Comparison
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Clinical, Mass spectrometry, Metabolites, Pharmaceutical

UHPLC/MS Analysis of Benzodiazepines and Glucuronide Metabolites on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Benzodiazepines and Glucuronide Metabolites on Titan™ C18
Keywords: High performance liquid chromatography, Mass spectrometry, Metabolites, Separation, Solvents

UHPLC/MS Analysis of Diazepam and Metabolites on Titan™ C18, Comparison of Flow Rate and Column Length

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Diazepam and Metabolites on Titan™ C18, Comparison of Flow Rate and Column Length
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Solvents

UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Sample preparations, Solid phase extractions

Peer-Reviewed Papers
15

References

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