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Y0000685 Sigma-Aldrich

Letrozole

European Pharmacopoeia (EP) Reference Standard

Synonym: 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards L - M, Pharmacopeia & Metrological Institutes Standards More...
InChI Key   HPJKCIUCZWXJDR-UHFFFAOYSA-N
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Letrozole is a third generation nonsteroidal aromatase inhibitor. It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the conversion of androgens to estrogens. Letrozole inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.

Packaging

Unit quantity: 70 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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08168 Timestrip Plus 8 °C
PHR1540 Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material

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