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Y0001553

Ciclesonide

European Pharmacopoeia (EP) Reference Standard

  • CAS Number 126544-47-6

  • Empirical Formula (Hill Notation) C32H44O7

  • Molecular Weight 540.69

  •  MDL number MFCD00866004

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards C - D, Pharmacopeia & Metrological Institutes Standards More...
biological source   synthetic
grade   pharmaceutical primary standard
Agency/Method   EP
form   neat
packaging   pkg of 150 mg
mfr. no.   EDQM
storage condition   protect from light
color   white
bp   665.0 °C/1.333 hPa (1229.0°F)
mp   209-211 °C (408—412°F)
solubility   water: <0.1 g/L
  acetone: soluble
  ethanol: soluble
density   1.23 g/cm3 at 20 °C (1.333 hPa)
Featured Industry   Pharmaceutical (small molecule)
format   neat
shipped in   ambient
storage temp.   2-8°C
SMILES string   C[C@@]12C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@]5([H])[C@]4(O[C@@](C6CCCCC6)([H])O5)C(COC(C(C)C)=O)=O)=CC(C=C1)=O
InChI   1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1
InChI key   LUKZNWIVRBCLON-GXOBDPJESA-N

Description

General description

Ciclesonide is a new-generation, non-halogenated glucocorticoid. It is a prodrug that releases an active primary metabolite, ciclesonide−active principle (CIC-AP), on enzymatic cleavage.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ciclesonide EP reference standard is used as a pharmaceutical primary standard to quantify the analyte in pharmaceutical formulations, bulk drug and metered-dose inhalers (MDIs) and dry powder ciclesonide inhalers using liquid chromatography (LC) based techniques.

Packaging

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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