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Y0001805

Pregabalin

European Pharmacopoeia (EP) Reference Standard

Synonym: (S)-3-(Aminomethyl)-5-methylhexanoic acid, CI-1008, PD-144723

  • CAS Number 148553-50-8

  • Empirical Formula (Hill Notation) C8H17NO2

  • Molecular Weight 159.23

  •  MDL number MFCD00917044

  •  PubChem Substance ID 329831580

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards P - R, Pharmacopeia & Metrological Institutes Standards More...
grade   pharmaceutical primary standard
mfr. no.   EDQM
drug control   USDEA Schedule I
Featured Industry   Pharmaceutical (small molecule)
storage temp.   2-8°C
SMILES string   CC(C)C[C@@](CN)([H])CC(O)=O
InChI   1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
InChI key   AYXYPKUFHZROOJ-ZETCQYMHSA-N
Gene Information   human ... CACNA1A(773), CACNA1B(774), CACNA1C(775), CACNA1D(776), CACNA1E(777), CACNA1F(778), CACNA1G(8913), CACNA1H(8912), CACNA1I(8911), CACNA1S(779), CACNA2D1(781), CACNA2D2(9254), CACNA2D3(55799), CACNA2D4(93589), CACNB1(782), CACNB2(783), CACNB3(784), CACNB4(785), CACNG1(786), CACNG2(10369), CACNG3(10368), CACNG4(27092), CACNG5(27091), CACNG6(59285), CACNG7(59284), CACNG8(59283)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Pregabalin is a lipophilic GABA analog/ligand at α2δ subunit of voltage-dependent Ca2+ channels. Pregabalin is an anticonvulsant, anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.

Packaging

Unit quantity: 260 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Target organs 
Central nervous system
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

UHPLC/MS Analysis of Anticonvulsants on Ascentis® Express HILIC

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Anticonvulsants on Ascentis® Express HILIC
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

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