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01148 Sigma-Aldrich

Sodium fluoride

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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Properties

Related Categories Chemical Synthesis, Essential Chemicals, Inorganic Salts, Research Essentials, Salts,
vapor pressure   1.4 mmHg ( 0 °C)
InChI Key   PUZPDOWCWNUUKD-UHFFFAOYSA-M
grade   puriss.
assay   98.5-100.5% (calc. to the dried substance)
quality   meets analytical specification of Ph. Eur., BP, USP
impurities   acidity or alkalinity, complies
  organic volatile impurities, complies (GC)
  residual solvents, complies
  ≤0.002% heavy metals (as Pb)
  ≤0.1% free alkali (as NaOH)
  ≤0.2% free acid (as HF)
  ≤0.2% sodium hexafluorosilicate (Na2SiF6)
loss   ≤0.5% loss on drying, 150 °C
mp   993 °C (lit.)
anion traces   chloride (Cl-): ≤10 mg/kg
  sulfate (SO42-): ≤200 mg/kg
cation traces   Fe: ≤50 mg/kg
suitability   complies for appearance of solution

Description

General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Application

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Contact with acids liberates very toxic gas.
RIDADR 
UN 1690 6.1 / PGIII
WGK Germany 
1
RTECS 
WB0350000

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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