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208566 Sigma-Aldrich

Titanium(IV) chloride

ReagentPlus®, 99.9% trace metals basis

Synonym: TTC, Titanium tetrachloride



Related Categories Acids, Acids & Bases, Alternative Energy, Catalysis and Inorganic Chemistry, Catalysts,
grade   ReagentPlus®
vapor pressure   50 mmHg ( 55 °C)
  9.6 mmHg ( 20 °C)
assay   99.9% trace metals basis
form   liquid
bp   135-136 °C(lit.)
mp   −25 °C (lit.)
density   1.73 g/mL at 20 °C(lit.)



1.5 kg in Sure/Seal™

200 g in Sure/Seal™


Activates pyrrolidines for improved conversion, via a modified Bouveault reaction, to the corresponding α,α-dimethylamines.

Along with sodium borohydride, it forms an effective reagent for the reduction of:
• carboxylic acid and acyl chloride to alcohols
• carboxamides, oximes and lactams to amines
• sulfoxides to sulfides

Titanium(IV) chloride (TiCl4) has been used as a precursor for the synthesis of Ag-TiO2@polyethylene glycol (PEG) nanoparticles. TiCl4 may also be used as one of the constituents to synthesize TiO2/Al2O3 binary oxide materials and N-(10-oxo-vinylanthracen-9-(10H)-ylidene)cyanamide.

General description

Titanium(IV) chloride participates in the Baylis-Hillman reaction of arylaldehydes with methyl vinyl ketone. Neutral solutions of TiCl4 having a pH in the range of 2.5 to 6.0 (prepared by the addition of magnesium oxide as a base) have been used for the synthesis of nanosized titanium dioxide.

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Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Supplemental Hazard Statements 
Corrosive to the respiratory tract., Reacts violently with water.
UN 1838 8
WGK Germany 


Certificate of Analysis

Certificate of Origin

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What is Product 208566, Titanium(IV) chloride, soluble in?
Per the Merck Index, Titanium(IV) Chloride is soluble in cold water and alcohol.
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