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213330 Sigma-Aldrich

Ammonium chloride

ACS reagent, ≥99.5%

Synonym: Salmiac

  • CAS Number 12125-02-9

  • Linear Formula NH4Cl

  • Molecular Weight 53.49

  •  Beilstein/REAXYS Number 4371014

  •  EC Number 235-186-4

  •  MDL number MFCD00011420

  •  eCl@ss 38050207

  •  PubChem Substance ID 329752144

  •  NACRES NA.21

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Properties

Related Categories Ammonium Salts, Chemical Synthesis, Development Quantities for Research, Essential Chemicals, Inorganic Salts,
Quality Level   200
grade   ACS reagent
vapor density   1.9 (vs air)
vapor pressure   1 mmHg ( 160.4 °C)
assay   ≥99.5%
impurities   ≤0.005% insolubles
ign. residue   ≤0.01%
pH   4.5-5.5 (25 °C, 5%)
mp   340 °C (subl.) (lit.)
anion traces   phosphate (PO43-): ≤2 ppm
  sulfate (SO42-): ≤0.002%
cation traces   Ca: ≤0.001%
  Fe: ≤2 ppm
  Mg: ≤5 ppm
  heavy metals: ≤5 ppm (by ICP-OES)
SMILES string   N.Cl
InChI   1S/ClH.H3N/h1H;1H3
InChI key   NLXLAEXVIDQMFP-UHFFFAOYSA-N

Description

General description

Crystals of ammonium chloride (NH4Cl) belong to the cubic crystal system. It can be synthesized by reacting HCl with aqueous ammonia solutions. NH4Cl is formed as a by-product during soda manufactured by Solvay process.

Application

Ammonium chloride (NH4Cl) has been used as one of the components of red blood cell (RBC) lysis buffer for use in various studies. It may be used as a catalyst in the preparation 3,4-dihydropyrimidin-2-(1H)-ones.
Inorganic ammonium ions (NH4+) effectively catalyze the aldol condensation of carbonyl compounds. It serves as a source of nitrogen during the preparation of trimethylamine hydrochloride (TMA·HCl).

Packaging

12, 25 kg in poly drum

2.5, 4×2.5 kg in poly bottle

25, 500, 6×500 g in poly bottle

50 kg in fiber drum

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
WGK Germany 
WGK 1
RTECS 
BP4550000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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