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27109 Sigma-Aldrich

Citric acid

meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance)

  • CAS Number 77-92-9

  • Linear Formula HOC(COOH)(CH2COOH)2

  • Molecular Weight 192.12

  •  Beilstein/REAXYS Number 782061

  •  EC Number 201-069-1

  •  MDL number MFCD00011669

  •  eCl@ss 39021801

  •  PubChem Substance ID 329752978

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Properties

Related Categories Analytical/Chromatography, Biochemicals and Reagents, Biological Buffers, Pharmacopoeia, Pharmacopoeia A-Z,
InChI Key   KRKNYBCHXYNGOX-UHFFFAOYSA-N
assay   99.5-100.5% (based on anhydrous substance)
form   grit
quality   anhydrous
  meets analytical specification of Ph. Eur., BP, USP, E330
expl. lim.   8 %, 65 °F
impurities   residual solvents, complies
  ≤0.0005% heavy metals (as Pb)
  ≤0.5% water (Karl Fischer)
ign. residue   ≤0.05% (as SO4)
pKa    (1) 3.13, (2) 4.76, (3) 6.4
mp   153-159 °C (lit.)
anion traces   chloride (Cl-): ≤50 ppm
  oxalate (as oxalic acid): ≤100 ppm
  sulfate (SO42-): ≤100 ppm
cation traces   As: ≤1 ppm
  Ca: ≤200 ppm
  Cu: ≤10 ppm
  Fe: ≤10 ppm
  Hg: ≤1 ppm
  Pb: ≤0.5 ppm
  Zn: ≤10 ppm
suitability   complies for appearance of solution
  complies for reaction against H2SO4
Gene Information   human ... SRC(6714)

Description

Application

Citric acid was used as a test reagent for studying whether the novel pyridazinylpiperazine analog TPRV-1 inhibitor can reduce cough reflex induced by citric acid and capsaicin in guinea pig.

Packaging

1, 6×1 kg in poly bottle

Biochem/physiol Actions

Citric acid in dietary form can augments absorption of aluminium in antacids. It also facilitates the phytoremediation of heavy metal contaminated soil and can transform cadmium into more transportable forms.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
GE7350000

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND

Setting the Standard for Solid Formulation
Protocols & Articles

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Peer-Reviewed Papers
15

References

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