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33120 Sigma-Aldrich

N,N-Dimethylformamide

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.8% (GC)

Synonym: DMF, NSC 5356

  • CAS Number 68-12-2

  • Linear Formula HCON(CH3)2

  • Molecular Weight 73.09

  •  Beilstein/REAXYS Number 605365

  •  EC Number 200-679-5

  •  MDL number MFCD00003284

  •  PubChem Substance ID 329754458

  •  NACRES NA.21

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Properties

Related Categories ACS Grade, Amber Glass Bottles, Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography,
Quality Level   200
grade   ACS reagent, reag. Ph. Eur.
vapor density   2.5 (vs air)
vapor pressure   2.7 mmHg ( 20 °C)
grade   puriss. p.a.
assay   ≥99.8% (GC)
autoignition temp.   833 °F
expl. lim.   15.2 %
impurities   ≤0.003% free acid (as CH3COOH)
  ≤0.005% free alkali (as NH3)
  ≤0.005% non-volatile matter
  ≤0.1% water (Karl Fischer)
color   APHA: ≤15
refractive index   n20/D 1.4290-1.4310
  n20/D 1.430 (lit.)
bp   152-154 °C
  153 °C (lit.)
mp   −61 °C (lit.)
density   0.948-0.950 g/mL at 20 °C
  0.944 g/mL (lit.)
cation traces   Al: ≤0.5 mg/kg
  B: ≤0.02 mg/kg
  Ba: ≤0.1 mg/kg
  Bi: ≤0.1 mg/kg
  Ca: ≤0.5 mg/kg
  Cd: ≤0.05 mg/kg
  Co: ≤0.02 mg/kg
  Cr: ≤0.02 mg/kg
  Cu: ≤0.02 mg/kg
  Fe: ≤0.1 mg/kg
  K: ≤0.5 mg/kg
  Li: ≥0.1 mg/kg
  Mg: ≤0.1 mg/kg
  Mn: ≤0.02 mg/kg
  Mo: ≤0.1 mg/kg
  Na: ≤1 mg/kg
  Ni: ≤0.02 mg/kg
  Pb: ≤0.1 mg/kg
  Sn: ≤0.1 mg/kg
  Sr: ≤0.1 mg/kg
  Zn: ≤0.1 mg/kg
SMILES string   [H]C(=O)N(C)C
InChI   1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
InChI key   ZMXDDKWLCZADIW-UHFFFAOYSA-N

Description

General description

N,N-Dimethylformamide (DMF) is commonly employed as a solvent for various organic reactions. DMF is a useful solvent employed for the isolation of chlorophyll from plant tissues. It is widely employed reagent in organic synthesis. It plays multiple roles in various reactions such as solvent, dehydrating agent, reducing agent as well as catalyst. It is a multipurpose building block for the synthesis of compounds containing O, -CO, -NMe2, -CONMe2, -Me, -CHO as functional groups.

Application

N,N-Dimethylformamide (DMF) may be employed as a solvent in the following studies:
• Extraction of chlorophyll containing pigments from the intact tissues of cotyledons of Cucumis sativus.
• Isolation of chlorophyll a from the cell cultures of unicellular marine algae.4
• As reducing agent and solvent for the preparation of Au@Ag core-shell nanocrystals.

Solvent for many hydrophobic organic compounds.

Packaging

2.5 L also available in PE-bottles

Other Notes

The article number 33120-4X2.5L-M will be discontinued. Please order the single bottle 33120-2.5L-M which is physically identical with the same exact specifications.
The article number 33120-4X2.5L-R will be discontinued. Please order the single bottle 33120-2.5L-R which is physically identical with the same exact specifications.
The article number 33120-6X1L-M will be discontinued. Please order the single bottle 33120-1L-M which is physically identical with the same exact specifications.
The article number 33120-6X1L-R will be discontinued. Please order the single bottle 33120-1L-R which is physically identical with the same exact specifications.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2265 3 / PGIII
WGK Germany 
2
RTECS 
LQ2100000
Flash Point(F) 
136.4 °F
Flash Point(C) 
58 °C

Dispensette™ S
Protocols & Articles

Articles

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Peer-Reviewed Papers
15

References

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