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34858 Sigma-Aldrich

Ethyl acetate

for HPLC, ≥99.7%

Synonym: EtOAc

  • CAS Number 141-78-6

  • Linear Formula CH3COOC2H5

  • Molecular Weight 88.11

  •  Beilstein/REAXYS Number 506104

  •  EC Number 205-500-4

  •  MDL number MFCD00009171

  •  PubChem Substance ID 329755067

  •  NACRES NA.21

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Properties

Related Categories Amber Glass Bottles, Analytical Reagents, Analytical/Chromatography, Chromatography Reagents & Solvents, Ethyl Acetate,
Quality Level   100
grade   for HPLC
vapor density   3 (20 °C, vs air)
vapor pressure   73 mmHg ( 20 °C)
assay   ≥99.7%
form   liquid
autoignition temp.   801 °F
expl. lim.   2.2-11.5 %, 38 °F
application(s)   GC/MS: suitable
  HPLC: suitable
impurities   ≤0.0005% non-volatile matter
  ≤0.005% free acid (as CH3COOH)
  ≤0.03% water (Karl Fischer)
refractive index   n20/D 1.3720 (lit.)
bp   76.5-77.5 °C (lit.)
mp   −84 °C (lit.)
density   0.902 g/mL at 25 °C (lit.)
UV absorption   λ: 255 nm Amax: ≤0.70
  λ: 260 nm Amax: ≤0.30
  λ: 270 nm Amax: ≤0.10
  λ: 300 nm Amax: ≤0.01
  λ: 400 nm Amax: ≤0.01
Featured Industry   Food and Beverages
SMILES string   CCOC(C)=O
InChI   1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
InChI key   XEKOWRVHYACXOJ-UHFFFAOYSA-N

Description

General description

Ethyl acetate is an effective alternate solvent of diethyl ether.

Application

Ethyl acetate has been used as solvent for the isolation of Rose hip (Rosa canina L., Rosaceae) powder, via sonication. It has been used as solvent for the abstraction of volatile thiols from wine for their quantitative estimation by gas chromatography/mass spectrometry (GC-MS).

Packaging

1 pkg in Pure-Pac™ 2

100 mL in glass bottle

200 L in Pure-Pac™ 1

1, 6×1, 2, 4×2, 4×2.5, 4, 4×4 L in glass bottle

18 L in Pure-Pac™ 1

20, 50 L in Pure-Pac™ 2

View returnable container options.

Other Notes

Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.

Important notice
• The article number 34858-4X2.5L will be discontinued. Please order the single bottle 34858-2.5L which is physically identical with the same exact specifications.
• The article number 34858-6X1L will be discontinued. Please order the single bottle 34858-1L which is physically identical with the same exact specifications.

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Legal Information

Pure-Pac is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Target organs 
Central nervous system
RIDADR 
UN1173 - class 3 - PG 2 - Ethyl acetate
WGK Germany 
WGK 1
RTECS 
AH5425000
Flash Point(F) 
24.8 °F
Flash Point(C) 
-4 °C

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Authenticity of Essential Oils: A HPTLC Fingerprint Method

Due to the increasing popularity of natural essential oils as products for personal care, pharmaceuticals, or for aromatherapy, the global market for essential oils is growing rapidly.1 Unfortunately...
Keywords: Addition reactions, Chromatography, Degradations, Derivatizations, Detection methods, Flame ionization detector, Gas chromatography, Nuclear magnetic resonance spectroscopy, Pharmaceutical, Solvents, Thin layer chromatography

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Peer-Reviewed Papers
15

References

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