EMAIL THIS PAGE TO A FRIEND
375810 Sigma-Aldrich

Periodic acid

ACS reagent, 99%

Purchase

Properties

Related Categories ACS Grade Acids & Bases, Acids, Acids & Bases, Analytical Reagents, Analytical Reagents for General Use,
Quality Level   200
grade   ACS reagent
assay   99%
  99.0-101.0% (ACS specification)
form   powder or crystals
application(s)   histology: suitable
impurities   ≤0.01% insolubles
  ≤0.01% other halogens
ign. residue   ≤0.01%
mp   122 °C (lit.)
solubility   water: soluble
anion traces   sulfate (SO42-): ≤0.01%
cation traces   Fe: ≤0.003%
  heavy metals: ≤0.005%
SMILES string   OI(O)(O)(O)(O)=O
InChI   1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)
InChI key   TWLXDPFBEPBAQB-UHFFFAOYSA-N

Description

General description

Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff’s reagent. Therefore periodic-acid-Schiff′s reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.

Application

Periodic acid may be used in the following reactions:
• Oxidation of alcohols to ketones and aldehydes.
• Oxidation hydroxylamine derivatives.
• Oxidation of arenes to quinones.
• Deprotection of the dithio- and oxathio-derivatives.
• Oxidative degradation of epoxidized natural rubber (ENR).
• Oxidation of urazoles and bis-urazoles to triazolinediones.
• Oxidative cleavage of glucosazone.

Packaging

25, 100 g in glass bottle

Safety & Documentation

Safety Information

Signal word 
Danger
Hazard statements 
Target organs 
Thyroid
RIDADR 
UN 3085 8(5.1) / PGII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Related Content

Molarity Calculator & Normality Calculator for Acids & Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution. To ...

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?