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443778 Sigma-Aldrich

1-Methyl-2-pyrrolidinone

ACS reagent, ≥99.0%

Synonym: 1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

  • CAS Number 872-50-4

  • Empirical Formula (Hill Notation) C5H9NO

  • Molecular Weight 99.13

  •  Beilstein/REAXYS Number 106420

  •  EC Number 212-828-1

  •  MDL number MFCD00003193

  •  PubChem Substance ID 329756501

  •  NACRES NA.21

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Properties

Related Categories ACS Grade, ACS Grade Solvents, ACS and Reagent Grade Solvents, Amber Glass Bottles, Carbon Steel Cans with NPT Threads,
Quality Level   200
grade   ACS reagent
vapor density   3.4 (vs air)
vapor pressure   0.29 mmHg ( 20 °C)
  0.99 mmHg ( 40 °C)
assay   ≥99.0%
form   liquid
autoignition temp.   518 °F
expl. lim.   9.5 %
impurities   ≤0.01% Free amines (as CH3NH2)
  ≤0.05% water
color   APHA: ≤50
refractive index   n20/D 1.47 (lit.)
pH   7.7-10.0 (20 °C, 100 g/L)
bp   202 °C (lit.)
  81-82 °C/10 mmHg (lit.)
mp   −24 °C (lit.)
solubility   acetone: miscible(lit.)
  alcohol: miscible(lit.)
  benzene: miscible(lit.)
  chloroform: miscible(lit.)
  ethyl acetate: miscible(lit.)
  water: miscible(lit.)
density   1.028 g/mL at 25 °C (lit.)
anion traces   chloride (Cl-): ≤1 ppm
SMILES string   CN1CCCC1=O
InChI   1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
InChI key   SECXISVLQFMRJM-UHFFFAOYSA-N

Description

Application

1-Methyl-2-pyrrolidinone may be used as:
• An alternative eluent to THF in the size exclusion chromatography (SEC) based resolution of coal-derived liquids.
• Reaction medium to prepare 2-aryl and 2-alkyl benzothiazoles.
• A solvent in the ultrasonic preparation of metal organic framework (MOF-177) crystals.
It may be used to synthesize single-phase chalcopyrite CuInSe2 nanocrystals and potassium 3-methyl-2-oxo-pyrrolidinenitronate.

Packaging

1, 2.5 L in glass bottle

View returnable container options.

18 L in steel drum

500 mL in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory system
WGK Germany 
WGK 1
RTECS 
UY5790000
Flash Point(F) 
195.8 °F - Pensky-Martens closed cup
Flash Point(C) 
91 °C - Pensky-Martens closed cup

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Peer-Reviewed Papers
15

References

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