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472301 Sigma-Aldrich

Dimethyl sulfoxide

ACS reagent, ≥99.9%

Synonym: DMSO

Purchase

Properties

Related Categories ACS Grade, ACS Grade Solvents, ACS and Reagent Grade Solvents, Amber Glass Bottles, Composite Drums,
grade   ACS reagent
vapor density   2.7 (vs air)
vapor pressure   0.42 mmHg ( 20 °C)
InChI Key   IAZDPXIOMUYVGZ-UHFFFAOYSA-N
assay   ≥99.9%
autoignition temp.   573 °F
expl. lim.   42 %, 63 °F
impurities   ≤0.001 meq/g Titr. acid
  ≤0.1% water
evapn. residue   ≤0.01%
color   clear colorless
refractive index   n20/D 1.479 (lit.)
bp   189 °C(lit.)
mp   16-19 °C (lit.)
density   1.10 g/mL (lit.)

Description

Application

Dimethyl sulfoxide (DMSO) has been used in the preparation of ethyl 4-[18F]fluorobenzoate. It has been used in the culture medium for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay.

Packaging

1, 6×1, 2.5, 4, 4×4 L in glass bottle

18 L in VerSA-Flow™

200 L in poly drum

4×4 L in poly bottle

50 L in Pure-Pac™ 2

100, 500, 6×500 mL in glass bottle

400 L in Pure-Pac™ 1

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Safety & Documentation

Safety Information

WGK Germany 
1
RTECS 
PV6210000
Flash Point(F) 
188.6 °F
Flash Point(C) 
87 °C

Documents

Certificate of Analysis

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Certificate of Origin

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Frequently Asked Questions

What is the molarity of DMSO?
DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.
What is the DMSO dissolved in?
DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.
Where does DMSO come from?
DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.
Does DMSO have any synthetic utility?
DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
Dimethyl sulfoxide (DMSO) should be a liquid. Why did it arrive as a solid?
DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
Is Dimethyl sulfoxide a sterile product?
No, this product is not considered sterile.Product Nos. D2560 and D2438 are sterile-filtered.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
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Peer-Reviewed Papers
15

References

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