• USA Home
  • 494488 - N,N-Dimethylformamide

EMAIL THIS PAGE TO A FRIEND
494488 Sigma-Aldrich

N,N-Dimethylformamide

biotech. grade, ≥99.9%

Synonym: DMF, NSC 5356

  • CAS Number 68-12-2

  • Linear Formula HCON(CH3)2

  • Molecular Weight 73.09

  •  Beilstein/REAXYS Number 605365

  •  EC Number 200-679-5

  •  MDL number MFCD00003284

  •  PubChem Substance ID 329757455

  •  NACRES NA.21

Purchase

Properties

Related Categories Amber Glass Bottles, Biotech, Biotech Solvents, Dimethylformamide (DMF), Returnable Containers,
Quality Level   200
grade   biotech. grade
  for peptide synthesis
vapor density   2.5 (vs air)
vapor pressure   2.7 mmHg ( 20 °C)
assay   ≥99.9%
autoignition temp.   833 °F
expl. lim.   15.2 %
impurities   ≤0.0005 meq/g Titr. acid
  ≤0.003 meq/g Titr. base
  ≤0.005% (water)
  <8 ppm Free amines as dimethylamine
evapn. residue   <0.0005%
refractive index   n20/D 1.430 (lit.)
bp   153 °C (lit.)
mp   −61 °C (lit.)
solubility   water: miscible
density   0.944 g/mL (lit.)
UV absorption   λ: 270 nm Amax: ≤1.0
  λ: 275 nm Amax: ≤0.30
  λ: 295 nm Amax: ≤0.10
  λ: 310 nm Amax: ≤0.05
  λ: 340 nm Amax: ≤0.01
  λ: 400 nm Amax: ≤0.01
SMILES string   [H]C(=O)N(C)C
InChI   1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
InChI key   ZMXDDKWLCZADIW-UHFFFAOYSA-N

Description

General description

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Application

N,N-dimethylformamide (DMF) has been used for the preparation of tetraformylcavitand precursor for generating octahedral nanocontainer.

Solvent for many hydrophobic organic compounds.

Packaging

1, 6×1, 2 L in Sure/Seal™

10 L in stainless steel drum

18 L in Pure-Pac™ 1

20 L in Nowpak™ II

20 L in Pure-Pac™ 2

View returnable container options.

56, 400 L in Pure-Pac™ 1

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2265 3 / PGIII
WGK Germany 
WGK 2
RTECS 
LQ2100000
Flash Point(F) 
135.5 °F - closed cup
Flash Point(C) 
57.5 °C - closed cup

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Dispensette™ S
Protocols & Articles

Articles

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?