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87368 Sigma-Aldrich

Tetrahydrofuran

contains 250 ppm BHT as inhibitor, puriss. p.a., ACS reagent, Reag. Ph. Eur., ≥99.9%

Synonym: Butylene oxide, Oxolane, Tetramethylene oxide

  • CAS Number 109-99-9

  • Empirical Formula (Hill Notation) C4H8O

  • Molecular Weight 72.11

  •  Beilstein/REAXYS Number 102391

  •  EC Number 203-726-8

  •  MDL number MFCD00005356

  •  PubChem Substance ID 329769580

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Properties

Related Categories Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography, Puriss p.a. ACS, T-Z, Puriss p.a. ACS More...
Quality Level   200
grade   ACS reagent
  Reag. Ph. Eur.
vapor density   2.5 (vs air)
vapor pressure   114 mmHg ( 15 °C)
  143 mmHg ( 20 °C)
grade   puriss. p.a.
assay   ≥99.9%
form   liquid
autoignition temp.   610 °F
contains   250 ppm BHT as inhibitor
  ~0.025% 2,6-di-tert-butyl-4-methylphenol as stabilizer
expl. lim.   1.8-11.8 %
application(s)   solid phase extraction (SPE): suitable
impurities   ≤0.001% free acid (as CH3COOH)
  ≤0.005% peroxides (as H2O2)
  ≤0.05% water
evapn. residue   ≤0.001%
refractive index   n20/D 1.407 (lit.)
  n20/D 1.407
pH   ~7
bp   65-67 °C (lit.)
mp   −108 °C (lit.)
density   0.887 g/mL at 20 °C
  0.889 g/mL at 25 °C (lit.)
cation traces   Al: ≤0.5 mg/kg
  B: ≤0.02 mg/kg
  Ba: ≤0.1 mg/kg
  Bi: ≤0.1 mg/kg
  Ca: ≤0.5 mg/kg
  Cd: ≤0.05 mg/kg
  Co: ≤0.02 mg/kg
  Cr: ≤0.02 mg/kg
  Cu: ≤0.02 mg/kg
  Fe: ≤0.1 mg/kg
  K: ≤0.5 mg/kg
  Li: ≤0.1 mg/kg
  Mg: ≤0.1 mg/kg
  Mn: ≤0.02 mg/kg
  Mo: ≤0.1 mg/kg
  Na: ≤0.5 mg/kg
  Ni: ≤0.02 mg/kg
  Pb: ≤0.1 mg/kg
  Sn: ≤0.1 mg/kg
  Sr: ≤0.1 mg/kg
  Zn: ≤0.1 mg/kg
SMILES string   C1CCOC1
InChI   1S/C4H8O/c1-2-4-5-3-1/h1-4H2
InChI key   WYURNTSHIVDZCO-UHFFFAOYSA-N

Description

General description

The product is tetrahydrofuran (THF) and it contains 250ppm BHT (Butylated hydroxytoluene) as an inhibitor. THF is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THF forms double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1,4-diol is formed as an intermediate during the synthesis of THF. Hot THF is useful for the dissolution of polyvinylidene chloride (PVDV).

Application

Tetrahydrofuran has been used as a solvent for the preparation of sol-gel solution for coating solid phase microextraction (SPME) fibers in a study.

It may be used for the dissolution of poly-ε-caprolactone (PCL) and 1,3-diaminopentane, during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds and acrylate-terminated poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32)- 1,3-diaminopentane (117) polymer, respectively.

Analysis Note

miscible with water and ethanol (96%) pass

Other Notes

Go to our Greener Alternative-2-Methyl Tetrahydrofuran - 155810

Go to our Greener Alternative-Cyclopentyl methylether - 675989

The article number 87368-6X1L-M will be discontinued. Please order the single bottle 87368-1L-M which is physically identical with the same exact specifications.

Sales restrictions may apply

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory system
Supplemental Hazard Statements 
EUH018 - EUH019
RIDADR 
UN 2056 3 / PGII
WGK Germany 
WGK 1
RTECS 
LU5950000
Protocols & Articles
Peer-Reviewed Papers
15

References

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