A1010 Sigma-Aldrich

Arsenic(III) oxide

ReagentPlus®, ≥99.0%

Synonym: Arsenic trioxide, Arsenous acid



Related Categories Arsenic, Cancer Research, Carcinogens, Cell Biology, Materials Science,
Quality Level   200
grade   ReagentPlus®
assay   ≥99.0%
SMILES string   O=[As]O[As]=O
InChI   1S/As2O3/c3-1-5-2-4


General description

Arsenic(III) oxide, also known as arsenic trioxide, is an amphoteric oxide that serves as a raw material for the synthesis of several arsenic-based compounds. It is utilized to decolorize glasses and enamels. Its efficacy in treating in acute promyelocytic leukaemia (APL) has been investigated.


Arsenic(III) oxide was used in a study detailing the effect of arsenic trioxide in combination with γ-irradiation to elucidate the hemoglobin (Hb).


1 kg in glass bottle

25, 100, 250 g in glass bottle

Biochem/physiol Actions

Very potent agent against acute promyelocytic leukemia (APL). Causes skin, lung and bladder cancer.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
UN 1561 6.1 / PGII
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How should product A1010, Arsenic(III) oxide be dissolved?
This product is soluble in 1 M NaOHat 66 mg/ml, with heat as needed, yielding a clear, colorless solution.This information can be found on the Product Information Sheet.
What is the solution stablity of A1010, Arsenic(III) oxide?
We do not have any solution stability data for product A1010. Thus it is best to make up fresh solutions of A1010.
What is the difference between Product Nos. A1010 and 202673, Arsenic(III) oxide?
Both products are Arsenic(III) oxide.The specifications for the products differ. Please see the Specification Sheets for details.
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