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04449 Sigma-Aldrich

O-(Octadecylphosphoryl)choline

≥98% (TLC)

Synonym: Octadecylphosphocholine, Phosphocholine octadecyl ester

  • CAS Number 65956-63-0

  • Empirical Formula (Hill Notation) C23H50NO4P

  • Molecular Weight 435.62

  •  Beilstein/REAXYS Number 3694312

  •  MDL number MFCD00171405

  •  PubChem Substance ID 329747927

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Properties

InChI Key   ZBNJXSZNWZUYCI-UHFFFAOYSA-N
assay   ≥98% (TLC)
storage temp.   −20°C

Description

Application

Antitumor phospholipid, induces apoptosis in three human leukemic cell lines.

Biochem/physiol Actions

C18-phosphocholine was the most potent alkylphosphocholine tested in inhibiting phosphatidylcholine biosynthesis. The effect is mediated by interrupting the translocation of the rate-limiting enzyme, CTP:phosphocholine cytidylyltransferase, to membranes, where it is active.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 04449.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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