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06863 Sigma-Aldrich

Glycoursodeoxycholic acid

≥96.0% (TLC)

Synonym: N-(3α,7β-Dihydroxy-5β-cholan-24-oyl)glycine, N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine, GUDCA, Glycylursodeoxycholic acid, Ursodeoxycholylglycine

  • CAS Number 64480-66-6

  • Empirical Formula (Hill Notation) C26H43NO5

  • Molecular Weight 449.62

  •  MDL number MFCD00137427

  •  PubChem Substance ID 329748294

  •  NACRES NA.25

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Properties

Related Categories Bile acids and Derivatives, Biochemicals and Reagents, Lipids, Sterol Lipids
InChI Key   GHCZAUBVMUEKKP-XROMFQGDSA-N
assay   ≥96.0% (TLC)

Description

Biochem/physiol Actions

Secondary bile acid derived from acyl glycine. Glycoursodeoxycholic Acid (GUDCA) is reported to have cytoprotective and anti-inflammatory effects.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 06863.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

Bile acids are increasingly recognized as playing an important signaling role in the control of immune response and energy metabolism. Recently, there has been interest in measuring bile acid concent...
Clare Glicksman, Michael Wright, Dave Bell, and Anders Fridström
Reporter US, Volume 33.1
Keywords: Bacterial conjugations, Clinical, High performance liquid chromatography, Hormones, Mass spectrometry, Metabolism, Separation, Thin layer chromatography

Peer-Reviewed Papers
15

References

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