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123M-1 Sigma-Aldrich

CD23 (1B12) Mouse Monoclonal Antibody

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Properties

Related Categories Alphabetical Index, Antibodies, CD0-CDC, Cell Marque Antibodies, Hematopathology,
conjugate   unconjugated
clone   1B12, monoclonal
biological source   mouse
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   2-8°C
packaging   vial of 0.1 mL concentrate (123M-14)
  vial of 0.5 mL concentrate (123M-15)
  bottle of 1.0 mL predilute (123M-17)
  vial of 1.0 mL concentrate (123M-16)
  bottle of 7.0 mL predilute (123M-18)
antibody form   culture supernatant
isotype   IgG1κ
antibody product type   primary antibodies
Quality Level   GMP-IVD
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
mfr. no.   Cell Marque
concentration   0.01-1 μg/mL (predilute)
  4-8 μg/mL (concentrate)
control   tonsil
visualization   membranous

Description

General description

This is a B-cell antibody that is useful to differentiate between B-CLL and B-SLL's that are CD23 positive from mantle cell lymphomas and small cleaved lymphomas that are CD23 negative. This antibody reacts with the antigen that is found on a subpopulation of peripheral blood cells, B lymphocytes and on EBV transformed B lymphoblastoid cell lines.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Quality


IVD

IVD

IVD

RUO

Linkage

CD23 Positive Control Slides, Product No. 123S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Preparation Note

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

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Note: This IFU may not apply to your specific product lot.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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Description

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123S CD23 Positive Control Slides, suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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