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15732 Sigma-Aldrich

D-Xylulose 5-phosphate lithium salt

≥90% (TLC)

  • CAS Number 2080295-99-2

  • Empirical Formula (Hill Notation) C5H11O8P · xLi+

  • Molecular Weight 230.11 (free acid basis)

  •  PubChem Substance ID 329750987

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates P-Z, Monosaccharide More...
InChI Key   FNZLKVNUWIIPSJ-RFZPGFLSSA-N
assay   ≥90% (TLC)
storage temp.   −20°C

Description

Biochem/physiol Actions

D-Xylulose 5-phosphate (D-Xu-5-P) is a metabolite of the hexose monophosphate pathway activating protein phosphatase 2A to mediate the acute effects of carbohydrate feeding on the glycolytic pathway, the coordinated control of enzymes required in fatty acid & triglyceride synthesis. D-Xylulose 5-phosphate is the signal for the coordinated control of lipogenesis. The elevation of D-Xylulose 5-phosphate is the coordinating signal that both acutely activates phosphofructokinase in glycolysis and promotes the action of the transcription factor ChREBP to increase transcription of the genes for the enzymes of lipogenesis, the hexose monophosphate shunt, and glycolysis, all of which are required for the de novo synthesis of fat.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

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Protocols & Articles

Articles

New Metabolomics Products

The availability of metabolites is an important element for progress in metabolomics. We have expanded our collection in an effort to provide you with the metabolites needed to advance your research.
Keywords: Metabolites, Metabolomics

Peer-Reviewed Papers
15

References

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