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  • 19589 - L-2,4-Diaminobutyric acid monohydrochloride

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19589 Sigma-Aldrich

L-2,4-Diaminobutyric acid monohydrochloride

≥98.0% (AT), ≥98.0% (TLC)

Synonym: DAB

  • CAS Number 1482-98-0

  • Empirical Formula (Hill Notation) C4H10N2O2 · HCl

  • Molecular Weight 154.60

  •  Beilstein/REAXYS Number 6086583

  •  MDL number MFCD01632031

  •  PubChem Substance ID 57647801

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Chemical Biology, Chemical Synthesis,
assay   ≥98.0% (AT)
  ≥98.0% (TLC)
form   powder or crystals
optical activity   [α]20/D +24±2°, c = 1.2% in 6 M HCl
application(s)   ligand binding assay: suitable
  peptide synthesis: suitable
color   white to off-white
mp   ≥220 °C (dec.) (lit.)
SMILES string   Cl[H].NCC[C@H](N)C(O)=O
InChI   1S/C4H10N2O2.ClH/c5-2-1-3(6)4(7)8;/h3H,1-2,5-6H2,(H,7,8);1H/t3-;/m0./s1
InChI key   BFPDKDOFOZVSLY-DFWYDOINSA-N

Description

Biochem/physiol Actions

L-2,4-Diaminobutyric acid (DAB) is a substrate of diaminobutyrate-pyruvate transaminase (EC 2.6.1.46), an enzyme involved in an alternative polyamine biosynthesis pathway in bacteria.

L-2,4-Diaminobutyric acid (DAB, DABA), a non-metabolized amino acid, is useful as a selective GABA uptake inhibitor which may have antitumour activity against hepatoma cells.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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