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  • 200-05N - Human Umbilical Vein Endothelial Cells: HUVEC, neonatal

200-05N Sigma-Aldrich

Human Umbilical Vein Endothelial Cells: HUVEC, neonatal

  •  NACRES NA.81



Related Categories Cell Culture, Endothelial Cells, Primary Cell Culture, Primary Cells
Quality Level   100
biological source   human umbilicus (normal veins)
packaging   pkg of 500,000 cells
growth mode   Adherent
karyotype   2n = 46
morphology   Endothelial
application(s)   cell culture | mammalian: suitable
relevant disease(s)   arthritis, cancer, cardiovascular diseases, diabetes
shipped in   dry ice
storage temp.   −196°C


General description

Human Umbilical Vein Endothelial Cells (HUVEC) provide a classic model system to study many aspects of endothelial function and disease, such as normal, abnormal and tumor-associated angiogenesis, oxidative stress, hypoxia and inflammation related pathways in endothelia under normal and pathological conditions, cardiovascular-related complications associated with various diseases, mode of action and cardiovascular protection effects of various compounds, etc.

Cell Line Origin



angiogenesis, cell signaling pathways, migration, invasion, growth factors, tube formation, vascular homeostasis, modulation of blood vessel tone, regulate cell grwoth and ECM deposition, vasculoregulation


Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO

Preparation Note

• Primary culture, >500,000 cells in Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Subculture Routine

Please refer to the HUVEC Culture Protocol.

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis (COA)

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Human Umbilical Vein Endothelial Cells (HUVEC) Culture Protocol

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