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200P-05N Sigma-Aldrich

Human Umbilical Vein Endothelial Cells: HUVEC, neonatal, pooled

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Properties

Related Categories Cell Culture, Endothelial Cells, Primary Cell Culture, Primary Cells
biological source   human umbilicus (normal veins)
growth mode   Adherent
karyotype   2n = 46
morphology   Endothelial
relevant disease(s)   arthritis, cancer, cardiovascular diseases, diabetes

Description

Application

angiogenesis, cell signaling pathways, migration, invasion, growth factors, tube formation, vascular homeostasis, modulation of blood vessel tone, regulate cell grwoth and ECM deposition, vasculoregulation

Preparation Note

• Primary culture, >500,000 cells in Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

General description

Human Umbilical Vein Endothelial Cells (HUVEC) provide a classic model system to study many aspects of endothelial function and disease, such as normal, abnormal and tumor-associated angiogenesis, oxidative stress, hypoxia and inflammation related pathways in endothelia under normal and pathological conditions, cardiovascular-related complications associated with various diseases, mode of action and cardiovascular protection effects of various compounds, etc.

Subculture Routine

Please refer to the HUVEC Culture Protocol.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


Cell Culture Guide

Milli-Q® Water Purification Solutions
Protocols & Articles

Protocols

Human Umbilical Vein Endothelial Cells (HUVEC) Culture Protocol

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