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223A-1 Sigma-Aldrich

A-1-Antitrypsin Rabbit Polyclonal Antibody

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Properties

Related Categories A1-AB, Alphabetical Index, Antibodies, Cell Marque Antibodies, Hematopathology,
Quality Level   GMP-IVD
biological source   rabbit
antibody form   Ig fraction of antiserum
antibody product type   primary antibodies
clone   polyclonal
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
form   buffered aqueous solution
species reactivity   human
packaging   vial of 0.1 mL concentrate (223A-14)
  vial of 0.5 mL concentrate (223A-15)
  bottle of 1.0 mL predilute (223A-17)
  vial of 1.0 mL concentrate (223A-16)
  bottle of 7.0 mL predilute (223A-18)
mfr. no.   Cell Marque
concentration   0.5-2 μg/mL (predilute)
  200-450 μg/mL (concentrate)
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:2000
conjugate   unconjugated
control   tonsil
shipped in   wet ice
storage temp.   2-8°C
visualization   cytoplasmic

Description

General description

The immunohistochemical staining of Alpha-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for A-1-Antitrypsin may also be used in detection of benign and malignant lesions of an histiocytic nature. Sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with portal fibrosis of uncertain etiology.

Linkage

A-1-Antitrypsin Positive Control Slides , Product No. 223S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Preparation Note

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Quality


IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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223S A-1-Antitrypsin Positive Control Slides, immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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