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236A-1 Sigma-Aldrich

CEA Rabbit Polyclonal Antibody

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Properties

Related Categories Alphabetical Index, Anatomic Pathology, Antibodies, CE-CH, Cell Marque Antibodies,
Quality Level   GMP-IVD
biological source   rabbit
antibody form   Ig fraction of antiserum
antibody product type   primary antibodies
clone   polyclonal
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
form   buffered aqueous solution
species reactivity   human
packaging   vial of 0.1 mL concentrate (236A-14)
  vial of 0.5 mL concentrate (236A-15)
  bottle of 1.0 mL predilute (236A-17)
  vial of 1.0 mL concentrate (236A-16)
  bottle of 7.0 mL predilute (236A-18)
mfr. no.   Cell Marque
concentration   0.01-1.0 μg/mL (predilute)
  2-200 μg/mL (concentrate)
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:500
conjugate   unconjugated
control   colon
shipped in   wet ice
storage temp.   2-8°C
visualization   cytoplasmic

Description

General description

Anti-CEA is employed essentially as a tool to assist in the distinction between adenocarcinoma and epithelioid malignant mesotheliomas, along with other markers such as those against calretinin, CK 5&6, CD15, HBME-1, MOC-31, and Ber-EP4. Another suggested use of anti-CEA is to immunophenotype various metastatic adenocarcinomas as a means of identifying their origin within a panel of different markers. Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix. Polyclonal anti-CEA is useful in staining hepatocellular carcinoma in a canalicular pattern.

Linkage

CEA Positive Control Slides, Product No. 236S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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236S CEA Positive Control Slides, immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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