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  • 246R-1 - E-cadherin (EP700Y) Rabbit Monoclonal Primary Antibody

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246R-1 Sigma-Aldrich

E-cadherin (EP700Y) Rabbit Monoclonal Primary Antibody

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, Breast / Gyn Pathology, Cell Marque Antibodies, E-EI,
conjugate   unconjugated
clone   EP700Y, monoclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   2-8°C
packaging   vial of 0.1 mL concentrate (246R-14)
  vial of 0.5 mL concentrate (246R-15)
  bottle of 1.0 mL predilute (246R-17)
  vial of 1.0 mL concentrate (246R-16)
  bottle of 7.0 mL predilute (246R-18)
antibody form   culture supernatant
isotype   IgG
Quality Level   500
antibody product type   primary antibodies
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
mfr. no.   Cell Marque
concentration   0.01-1.0 μg/mL (predilute)
  1-35 μg/mL (concentrate)
control   breast
visualization   membranous

Description

General description

E-cadherin is an adhesion protein that is expressed in cells of epithelial lineage. Anti-E-cadherin stains positively in glandular epithelium as well as adenocarcinomas of the lung, G.I. tract, and ovary. Another application involves the differentiation of ductal (which is membrane staining) vs. lobular cancer of the breast (which is cytoplasmic staining). It has also been shown to be positive in some thyroid carcinomas. A combination of E-cadherin and p120 catenin helps distinguish ductal carcinoma of the breast from lobular carcinoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Quality


IVD

IVD

IVD

RUO

Linkage

E-cadherin Positive Control Slides, Product No. 246S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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246S E-cadherin Positive Control Slides, suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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