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27662 Sigma-Aldrich

Collagen from bovine achilles tendon

lyophilized

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Properties

Related Categories Biochemicals and Reagents, Collagen, Proteins and Derivatives, Structural Proteins
biological source   bovine Achilles tendon
form   fibers
quality   lyophilized
application(s)   sample preparation: suitable
storage temp.   2-8°C
Gene Information   cow ... COL1A1(282187)

Description

General description

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Collagen terminology using the Bornstein and Traub designation originates from the reference; Bornstein, P. and Traub, W. The Proteins, (1979) 4, 411-605

Application

Bovine achilles tendon collagen was used in a study of plant extracts as inhibitors of MMP-collagenases, the putative active agents in the breakdown of cartilage in osteoarthritis and rheumatoid arthritis.

Other Notes

Sales restrictions may apply

The collagens: An overview and update

Safety & Documentation

Safety Information

Personal Protective Equipment 
WGK Germany 
1

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How should Product 27662, Collagen from bovine, be reconstituted?
This product is an insoluble collagen preparation. It is insoluble in water, aqueous buffers, dilute acid, and organic solvents. A suspension can be prepared in 50 mM TES buffer, pH 7.4 with 0.36 mM calcium chloride, but not a clear solution.
What "type" of collagen does Product 27662, Collagen from bovine, consist of?
This collagen is classified as Bornstein and Traub type I.
What is the structure of Product 27662, Collagen from bovine?
The amino acid sequence of the primary structure is mainly a repeating motif with glycine in every third position, and a proline or 4-hydroxyproline frequently preceding the glycine residue.
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Protocols & Articles
Peer-Reviewed Papers
15

References

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