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  • 280R-1 - Mammaglobin (31A5) Rabbit Monoclonal Antibody

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280R-1 Sigma-Aldrich

Mammaglobin (31A5) Rabbit Monoclonal Antibody

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, Breast / Gyn Pathology, Cell Marque Antibodies, M1-MAR,
conjugate   unconjugated
clone   31A5, monoclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   2-8°C
packaging   vial of 0.1 mL concentrate (280R-14)
  vial of 0.5 mL concentrate (280R-15)
  bottle of 1.0 mL predilute (280R-17)
  vial of 1.0 mL concentrate (280R-16)
  bottle of 7.0 mL predilute (280R-18)
antibody form   culture supernatant
isotype   IgG
Quality Level   100
  500
antibody product type   primary antibodies
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
mfr. no.   Cell Marque
concentration   0.01-1 μg/mL (predilute)
  2.5-250 μg/mL (concentrate)
control   breast carcinoma
visualization   cytoplasmic

Description

General description

Mammaglobin (10 kD) is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin mRNA is present in high levels in human breast cancer cell lines, which has been shown to be a sensitive marker of breast cancer. When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84% has been achieved. Anti-mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Quality


IVD

IVD

IVD

RUO

Linkage

Mammaglobin Positive Control Slides , Product No. 280S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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280S Mammaglobin Positive Control Slides, suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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