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282200 Sigma-Aldrich

Galangin

autophagy inducing flavonoid

Synonym: 3,5,7-Trihydroxyflavone, Norizalpinin

  • CAS Number 548-83-4

  • Empirical Formula (Hill Notation) C15H10O5

  • Molecular Weight 270.24

  •  Beilstein Registry Number 272179

  •  EC Number 208-960-4

  •  MDL number MFCD00006833

  •  PubChem Substance ID 57648294

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Properties

Related Categories Cell Biology, Flavonoids, Flavonols, and Flavanols, Nutrition Research, Phytochemicals by Chemical Classification
InChI Key   VCCRNZQBSJXYJD-UHFFFAOYSA-N
mp   214-215 °C (lit.)
Gene Information   human ... ADORA2A(135), ADORA3(140), CYP1A2(1544)
rat ... Adora1(29290), Adora2a(25369)

Description

Packaging

25, 100 mg in glass bottle

Biochem/physiol Actions

Galangin is a flavonoid found in medicinal herbs. An inhibitor of cancer cell proliferation, galangin is used to study mechanisms of genotoxicity induced by molecules such as benzo[a]pyrene (B(a)P) and oxidation. Galangin may be used to study the expression of the cytochrome P450 isozyme CYP1A1 and to inhibit CYP1A1 activity. Autophagy inducer.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 282200.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
LK9275500

Documents

Certificate of Analysis

Certificate of Origin


Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

UHPLC Analysis of Galangin on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Galangin on Titan™ C18
Keywords: Chromatography, Mass spectrometry, Pharmaceutical

Peer-Reviewed Papers
15

References

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