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30078 Sigma-Aldrich

Cysteamine hydrochloride

BioXtra

Synonym: β-Mercapto­ethylamine hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, 2-Amino­ethane­thiol hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

  • CAS Number 156-57-0

  • Linear Formula HSCH2CH2NH2 · HCl

  • Molecular Weight 113.61

  •  Beilstein/REAXYS Number 3590083

  •  EC Number 205-858-1

  •  MDL number MFCD00012904

  •  PubChem Substance ID 329753424

  •  NACRES NA.51

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Properties

Related Categories Alphabetical, Biochemicals and Reagents, Denaturation, Disulfide Bridge Cleavage Reagents
Quality Level   200
product line   BioXtra
pH   3.5-5.0 (25 °C, 1 M in H2O)
mp   67-71 °C
solubility   H2O: 1 m at 20 °C, clear, colorless
anion traces   sulfate (SO42-): ≤50 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.5 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤50 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
absorption   cut-off at 270 nm in H2O at 1 M
λ   1 M in H2O
UV absorption   λ: 280 nm Amax: ≤0.3
storage temp.   2-8°C
SMILES string   Cl[H].NCCS
InChI   1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
InChI key   OGMADIBCHLQMIP-UHFFFAOYSA-N

Description

General description

Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine.

Application

Cysteamine is used in a wide range of applications such as regulation of gene expression, depletion of somatostatin and coating of nanoparticles. It may be used to study the potential value of cystine in metabolism disorders such as cystinosis. Cysteamine may be used as a redox sensitive component in biosensor development.

Other Notes

Aminothiol radioprotector; Inducer of duodenal ulcers in rodents; Depletes somatostatin concentration in rat tissues.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 3335
WGK Germany 
WGK 3
RTECS 
KJ0200000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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