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30320 Sigma-Aldrich

Cytidine 5′-triphosphate disodium salt hydrate

≥90.0% (HPLC)

Synonym: 5-CTP-Na2, CTP

  • CAS Number 652154-13-7

  • Empirical Formula (Hill Notation) C9H14N3Na2O14P3 · xH2O

  • Molecular Weight 527.12 (anhydrous basis)

  •  Beilstein Registry Number 3582735

  •  MDL number MFCD00150809

  •  PubChem Substance ID 57648425

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotides More...
InChI Key   IJMSOWKYYIROGP-LLWADOMFSA-L
assay   ≥90.0% (HPLC)
impurities   ≤12% water
solubility   H2O: 50 mg/mL, clear, colorless
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

100, 500 mg in poly bottle

Application

Cytidine 5γ-triphosphate (CTP) is used to synthesize RNA by various RNA polymerases. Cytidine 5γ-triphosphate (CTP) is a substrate for CMP-neuNAc synthetase(s) which produce CMP-neuNAc used in sialylation reactions. As a substrate of CTP:phosphocholine cytidylyltransferase(s) (CT), CTP supports the formation of phosphatidylcholine via the formation of CDP-choline.

Cytidine 5′-triphosphate disodium salt hydrate has been used:
• in the oligonucleotide synthesis for silver nanoclusters interaction studies
• as an anion source for fluorescence emission and titration curve-analysis of hypocrellin A-zinc(II) complex
• in fluorescence emission experiments of copper(II)–2,6-bis(2-benzimidazolyl)pyridine complex

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) is essential for the synthesis of DNA and is a mediator of many physiological processes in living systems. It is crucial for the dolichol phosphorylation, cholesterol transport and is involved in the allosteric regulation of aspartate transcarbamylase. It is also used in the treatment of disease related brain.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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