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30970 Sigma-Aldrich

Sodium deoxycholate

BioXtra, ≥98.0% (dry matter, NT)

Synonym: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

  • CAS Number 302-95-4

  • Empirical Formula (Hill Notation) C24H39NaO4

  • Molecular Weight 414.55

  •  Beilstein/REAXYS Number 3581950

  •  EC Number 206-132-7

  •  MDL number MFCD00064139

  •  PubChem Substance ID 57648497

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Properties

Related Categories Anionic Detergents, Antigen-Vaccine Preparation, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents,
Quality Level   PREMIUM
description   anionic
InChI Key   FHHPUSMSKHSNKW-SMOYURAASA-M
product line   BioXtra
assay   ≥98.0% (dry matter, NT)
optical activity   [α]20/D +44±2°, c = 2% in H2O
mol wt   micellar avg mol wt 1200-5000
aggregation number   3-12
application(s)   DNA purification: suitable
  RNA purification: suitable
  electrophoresis: suitable
impurities   ≤1% cholic acid (HPLC)
  ≤6% water
CMC   2-6 mM (20-25°C)
solubility   water: soluble 1 gm in 10 ml, clear, colorless to very faintly yellow
cation traces   Ca: ≤500 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤10 mg/kg
  Mg: ≤10 mg/kg
  Mn: ≤5 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤10 mg/kg
  Zn: ≤5 mg/kg
HLB   16

Description

Application

Sodium deoxycholate has been used for preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins.

Packaging

25, 100, 500 g in poly bottle

Biochem/physiol Actions

Sodium deoxycholate is a bile salt that stimulates the apical to basolateral accumulation of epirubicin in Caco-2 cells as well as increased serosal absorption of epirubicin in the rat jejunum and ileum. Sodium deoxycholate dissociates histones II from DNA as well as causes lysis of the viral membrane.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
FZ2250000

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

Development of a Simple and Rapid Digestion Protocol for Proteomics Sample Preparation

Reliable and reproducible results in mass spectrometry proteomics analyses are highly dependent on robust sample preparation. Sample preparation workflows are often cumbersome and generally involve c...
Zhiyun Cao, Amber Henry, Judy Boland, Nicolas Caffarelli, Jeffrey Turner, Kevin Ray
Keywords: Alkylations, Cell disruption, Detergents, Digestions, Mass spectrometry, Nucleic acid denaturation, Proteomics, Reductions, Sample preparations

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Protocols

LPL Activity Assay Protocol

The kit is sufficient for 100 assays in 200 µL total assay volume. Substrate Emulsion                                    0.125 mL Catalog Number MAK109A LPL Standard, 75.7 mM                         ...
Keywords: Sample preparations

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