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  • 314R-1 - Cytokeratin 14 (SP53) Rabbit Monoclonal Antibody

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314R-1 Sigma-Aldrich

Cytokeratin 14 (SP53) Rabbit Monoclonal Antibody

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Anatomic Pathology, Antibodies, CT-CZ, Cell Marque Antibodies,
conjugate   unconjugated
clone   SP53, monoclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
species reactivity   human
form   buffered aqueous solution
shipped in   wet ice
storage temp.   2-8°C
packaging   vial of 0.1 mL concentrate (314R-14)
  vial of 0.5 mL concentrate (314R-15)
  bottle of 1.0 mL predilute (314R-17)
  vial of 1.0 mL concentrate (314R-16)
  bottle of 7.0 mL predilute (314R-18)
antibody form   culture supernatant
isotype   IgG
Quality Level   100
  500
antibody product type   primary antibodies
description   For In Vitro Diagnostic Use in Select Regions (See Chart)
mfr. no.   Cell Marque
concentration   1.0-5.0 μg/mL (predilute)
  35-70 μg/mL (concentrate)
control   squamous carcinoma
visualization   cytoplasmic

Description

General description

Cytokeratin 14 is a 50 kDa polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. This antibody has also been useful in separating oncocytic tumors of the kidney from its renal mimics, as well as in identifying metaplastic carcinomas of the breast. Anti-CK14 is particularly valuable in identifying basal-like carcinoma of the breast.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Quality


IVD

IVD

IVD

RUO

Linkage

Cytokeratin 14 Positive Control Slides, Product No. 314S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Preparation Note

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Note: This requires a keycode which can be found on your packaging or product label.

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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Description

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314S Cytokeratin 14 Positive Control Slides, suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) 

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